The formulation is a transparent, homogeneous, viscoelastic gel based on a unique combination of biotechnologically derived and physiologically compatible components:
- Recombinant human collagen (Rh-collagen, α1 chain polypeptide of type I collagen) – a biomimetic molecule identical to naturally occurring human collagen. It is produced through controlled biotechnological fermentation using modified Pichia pastoris yeast strains, then purified and stabilised for medical use. Rh-collagen supports fibroblast activity and stimulates endogenous collagen synthesis, demonstrating excellent tissue compatibility.
- Non-cross-linked high-molecular-weight hyaluronic acid – provides intensive hydration, supports skin elasticity and density, and creates optimal conditions for dermal regeneration at the cellular level.
- Carboxymethylcellulose (CMC) – acts as a stabilising and supporting agent, improving gel distribution and prolonging the activity of the active ingredients.
Due to its non-volumising and physiologically progressive mechanism of action, Karisma Rh Collagen Face promotes gradual skin restructuring. The biostimulatory effect increases with each session, reaching optimal results by the end of the treatment course.
Karisma Rh Collagen Face is a CE-marked medical device intended exclusively for professional use in accordance with EU and German medical device regulations.
Karisma Rh Collagen Face is indicated for the correction and prevention of early skin ageing signs related to reduced skin quality and structural integrity. Typical indications include:
- Reduced skin firmness and elasticity
- Dull, tired and dehydrated appearance
- Uneven skin tone and texture
- Fine lines and superficial wrinkles
The product is suitable for patients aged 30+ and can be used on the face, neck, décolleté and the dorsal surface of the hands.
With course-based application, Karisma Rh Collagen Face supports dermal matrix strengthening and long-lasting hydration, resulting in:
- Improved skin turgor and firmness
- Smoothing of fine wrinkles and lines
- Reduction in the appearance of post-acne scars and stretch marks
- Improvement of facial and lip contours without volumisation
- Reduction of dark circles and puffiness in the periorbital area
- Relief from dryness, flaking and tightness
- Restoration of a healthy, radiant complexion
A standard treatment protocol consists of 3–5 sessions at intervals of 3–4 weeks. Initial improvements are usually visible after 2–3 treatments, with results lasting approximately 6–9 months, depending on individual skin condition and lifestyle factors.